POST. MIKROBIOL.,
2002, 41, 1, 51-69
http://www.pm.microbiology.pl

WYSPY PATOGENNOSCI

Joanna Mokracka, Ryszard Koczura,
Adam Kaznowski

1. Wstęp. 2. Ogólna charakterystyka wysp patogenności. 2.1. Wyspy genomowe a wyspy patogenności. 3. Występowanie wysp patogenności. 4. Ważniejsze bakteryjne wyspy patogenności. 4.1. Escherichia coli. 4.2. Yersinia spp. 4.3. Salmonella spp. 4.4. Shigella spp. 4.5. Vibrio cholerae. 4.6. Helicobacter pylori. 5. Podsumowanie

Pathogenicity islands

Abstract:      Recent studies on bacterial virulence mechanisms revealed that some virulence determinants are located within so-called pathogenicity islands (PAls). That term has been invented to describe large, often unstable DNA regions harboring virulence and mobility genes, usually flanked by direct repeats. PAls allow bacteria to acquire or lose large amounts of DNA, and are regarded as elements involved in bacterial macroevolution. The PAts of several bacterial species are reviewed herein.

1. Introduction. 2. Common characteristics of pathogenicity islands. 2.1. Genomic islands and pathogenicity islands. 3. Occurrence of pathogenicity islands. 4. More important bacterial pathogenicity islands. 4.1. Escherichia coli. 4.2. Yersinia spp. 4.3. Salmonella spp. 4.4. Shigella spp. 4.5. Vibrio cholerae. 4.6. Helicobacter pylori. 5. Summary

Zakład Mikrobiologii, Uniwersytet im. A. Mickiewicza
ul. Fredry 10, 61-701 Poznań
e-mail: amok@amu.edu.pl

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