22 October 2025
Abstract: Akkermansia muciniphila is a gut bacterium that has recently attracted considerable attention in microbiota research. Its presence in the gut is associated with improved metabolic health, enhanced gut barrier integrity, and modulation of the immune system. However, potential risks related to its abundance under certain pathological conditions have also been noted. As A. muciniphila emerges as a candidate for next-generation probiotics, evaluating whether current data support its therapeutic use is crucial. In this review, we analyze the available literature to outline the beneficial effects of A. muciniphila on the host and critically assess its potential as a probiotic.
