Staphylococcus pseudintermedius – trudno rozpoznawalny patogen

Staphylococcus pseudintermedius – a pathogen difficult to identify
M. Kizerwetter-Świda, D. Chrobak-Chmiel, M. Rzewuska, M. Binek

1. Wstęp. 2. Grupa Staphylococcus intermedius (SIG, Staphylococcus intermedius group). 3. Występowanie S. pseudintermedius. 4. Potencjał zoonotyczny S. pseudintermedius. 5. Identyfikacja. 6. Typowanie genetyczne. 7. Wykrywanie oporności na meticylinę u szczepów S. pseudintermedius – metody fenotypowe. 8. Wykrywanie oporności na meticylinę u S. pseudintermedius – metody genotypowe. 9. S. pseudintermedius – oporność na antybiotyki i chemioterpautyki. 10. Podsumowanie

Abstract: Staphylococcus pseudintermedius has recently been described as a member of the Staphylococcus genus. Three closely related staphylococci (Staphylococcus pseudintermedius, Staphylococcus intermedius and Staphylococcus delphini) with very similar phenotypic characteristics form the S. intermedius group (SIG). In fact, majority of strains previously recognized as S. intermedius isolated from dogs were reclassified to the species S. pseudintermedius. Within the SIG, S. pseudintermedius represents the major pathogenic species and is involved in a wide variety of infections, mainly in dogs, but also in other animal species and humans. Recently, an increase has been observed in the frequency of infections caused by methicillin-resistant S. pseudintermedius (MSRP) in animals, especially in dogs and humans. The identification of S. pseudintermedius in veterinary laboratories is usually not difficult, however, in laboratories working with materials collected from people the risk of misidentification is high. Moreover, the demonstration of the mecA gene may be a challenge in diagnostic laboratories. The objective of this review is to summarize the current knowledge of Staphylococcus pseudintermedius, including MRSP, with the emphasis on taxonomy, occurrence and diagnostics. Furthermore, this review present also the genetic basis of antimicrobial resistance in S. pseudintermedius.

1. Introduction. 2. Staphylococcus intermedius group (SIG) 3. The occurrence of S. pseudintermedius. 4. Zoonotic potential of S. pseudintermedius. 5. Identification. 6. Genetic typing. 7. Detection of methicillin resistance in S. pseudintermedius – phenotypic methods. 8. Detection of methicillin resistance in S. pseudintermedius – genotypic methods. 9. S. pseudintermedius – resistance to antimicrobials. 10. Summary