OPRYSZCZKOWE ZAPALENIE MÓZGU


Herpes simplex encephalitis (HSE)
M. Popiel, E. Wietrak, T. Laskus

Attachments

1. Wstęp. 2. Wirusowe zapalenia mózgu. 3. Opryszczkowe zapalenie mózgu. 3.1. Epidemiologia. 3.2. Patogeneza. 3.3. Objawy kliniczne. 3.4. Diagnostyka. 3.4.1. Reakcja łańcuchowej polimerazy (PCR – Polymerase Chain Reaction). 3.4.2. Badania serologiczne. 3.5. Leczenie. 4. Podsumowanie.

Abstract: Encephalitis is a severe neurological disease, usually caused by viral infection. Most cases of viral encephalitis have unclear etiology. Herpes simplex encephalitis (HSE) comprises about 10–20% of cases of viral encephalitis, and is the most common cause of encephalitis with known etiology. HSE is associated with 30% mortality in treated patients, while mortality in the untreated patients is as high as 70%. Rapid and correct diagnosis of HSE is essential for fast introduction of right treatment, which leads to significant reduction in mortality and lowers the risk of neurological complications.

1. Introduction. 2. Viral encephalitis. 3. Herpes simplex encephalitis. 3.1. Epidemiology. 3.2. Pathogenesis. 3.3. Clinical symptoms. 3.4. Diagnostics. 3.4.1. Polymerase Chain Reaction. 3.4.2. Serology. 3.5. Treatment. 4. Summary