Mikrobiom układu oddechowego w warunkach fizjologicznych i patologicznych

The respiratory tract microbiota in physiological and pathological conditions
M. Malinowska, B. Tokarz-Deptuła, W. Deptuła

1. Wprowadzenie. 2. Charakterystyka mikrobiomu dróg oddechowych w warunkach fizjologicznych. 3. Mikrobiom dróg oddechowych w warunkach patologicznych. 4. Podsumowanie

Abstract: The human body is inhabited by millions of microorganisms, residing on and in the skin, in the gastrointestinal tract, on the mucous membranes of the upper respiratory tract and in the vagina. Lower respiratory tract has considered to be free of bacteria, but the current research on microorganisms, using 16S rRNA gene sequencing, led to the identification of the microbiome of this unique environment. It has been demonstrated that the bacterial flora of the lower respiratory tract is significantly different from that of the upper respiratory tract. Moreover, a difference in the microbiome of the lower respiratory tract of healthy individuals and patients suffering from chronic diseases such as asthma and chronic obstructive pulmonary disease (COPD), has been shown.

1. Introduction. 2. Characteristics of the respiratory tracts microbiota in physiological conditions. 3. Respiratory tract microbiota in pathological conditions. 4. Summary