Browsing tag: diagnosis

GONOCOCCI – PATHOGENS OF GROWING IMPORTANCE. PART 1. CURRENT DATA ON DIAGNOSTICS, GENOTYPING AND THERAPY.


Joanna Białecka, Katarzyna Rak and Aneta Kiecka

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Abstract: Neisseria gonorrhoeae is an aetiological agent of gonorrhoea, which is a sexually transmitted disease (STD), a public health challenge worldwide. Gonorrhoea is undoubtedly a serious health risk, especially for women, due to its often asymptomatic course and the possibility of upper genital tract complications such as pelvic inflammatory disease (PID), which can result in infertility. The data show that the diagnostic method for N. gonorrhoeae should be specific, simple, sensitive, rapid and inexpensive. Currently, phenotypic identification methods have been dominated by NAAT methods, which allow detection and identification of gonococcus directly in the clinical specimen. However, up today molecular methods do not allow full determination of drug susceptibility.

ALKHUMRA HEMORRHAGIC FEVER VIRUS (AHFV): CURRENT STATUS AND FUTURE PROSPECTS


Leena Esam Azhar

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Abstract: The objective of this review to summarize the current status of information about the Alkhumra hemorrhagic fever caused by Alkhumra hemorrhagic fever virus an Arboviral infection. This virus was identified in Alkhumra district of Jeddah, Saudi Arabia in 1995 from a butcher patient. The infected individual develops symptoms febrile flu-like illness, hemorrhagic manifestations and less like encephalitis. Several cases have been reported from various locations of Saudi Arabia and a few from Egypt and is further expanding in tropical and subtropical regions of Western Asia. The virus is transmitted to human by direct contact to animal, raw meat, and biproducts as well as either tick or mosquito bites. Based on the recent status, a great concern of public health was raised with the AHFV epidemics and infection. Currently, there is no effective vaccine and antiviral therapeutics against AHFV. So, there is an urgent need to design and develop an effective preventive measure using interdisciplinary approach. This review will provide the status of research work based on the latest published information about AHFV. The provided information will be highly useful to design the effective preventive measures to control the disease in the Kingdom of Saudi Arabia.

CANDIDA AURIS: WHAT DO WE KNOW ABOUT THE MOST ENIGMATIC PATHOGEN OF THE 21ST CENTURY?


Agnieszka Bogut

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Abstract: Candida auris is a new fungal pathogen whose clinical significance has dramatically increased within recent years. Major issues related to this species include its rapid global spread and high epidemic potential, resilience and persistence in the hospital environment favoured by its resistance against certain disinfectants, horizontal transmission; possibility of persistent colonization, challenging labora-tory identification based on conventional biochemical methods, multidrug resistance as well as the need for implementation of restrictive and expensive prevention and control measures. This review raises the above mentioned issues and compiles recent findings regarding this microorganism.